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A viewer asks: “Being aware of Creator’s previous answers on Vitamin D3 supplementation I was shocked to discover a paper from 2014 “A Statistical Error in the Estimation of the Recommended Dietary Allowance for Vitamin D”. The paper claims that the Recommended Daily Allowance advocated by the Institute of Medicine for Vitamin D was incorrectly calculated! In fact, analyzing the data correctly, nearly 9000 IUs per day are required to achieve target levels (600 IU per day is the USA recommended level). I was struck by how closely the 9000 IU figure matched Creator’s “daily doses of 5,000 to 10,000 IU vitamin D3 will rarely be harmful.” What is Creator’s perspective on this “miscalculation” coming to light?”
ClosedNicola asked 2 weeks ago • 
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A British group reported recently that administration of vitamin D2, which is converted to vitamin D3 by the body, may be disadvantageous. A review of random controlled trials showed that taking vitamin D2 can lead to a decrease in vitamin D3 levels, the more active form generated by sunlight exposure. The research indicates that D2 supplementation may not only be less effective, but can also lead to lower concentrations of D3 in the circulation. [Emily I G Brown, et al. Effect of Vitamin D2 Supplementation on 25-Hydroxyvitamin D3 Status: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutr Rev, 2025 Sep 18:nuaf166.doi: 10.1093/nutrit/nuaf166]. Is this an accurate and meaningful assessment? What is most important for us to know?
ClosedNicola asked 2 weeks ago • 
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A viewer asks: “Is Manuka honey worthy of our nutrition dollars? Here’s a summary of benefits from a Brave search (saw nothing on the Creator database): Manuka honey offers a range of potential health benefits due to its unique antibacterial, antiviral, anti-inflammatory, and antioxidant properties. It is particularly noted for its ability to support wound and burn healing, with research indicating it can promote tissue regeneration, reduce pain, and help prevent infections, including those caused by antibiotic-resistant strains like MRSA. The U.S. Food and Drug Administration (FDA) has approved its use for wound treatment, and medical-grade Manuka honey is often used as a sterile dressing for minor wounds and leg ulcers. For oral health, Manuka honey may help reduce dental plaque buildup, potentially preventing gingivitis and other periodontal diseases. It can also soothe sore throats and help relieve coughs, with clinical trials supporting its effectiveness in alleviating these symptoms. In terms of digestive health, Manuka honey may support gut health by acting as a prebiotic and helping to manage conditions like stomach ulcers and acid reflux. Manuka honey is also used for skin care, where it can hydrate the skin, manage acne, and help with conditions like eczema and dermatitis. Its application as a topical treatment for dry, irritated, or sensitive skin, including as a facial mask or lip balm, is common. Some studies suggest it may help reduce the signs of aging, such as fine lines and wrinkles. Additionally, Manuka honey may support overall immunity, provide natural energy, and serve as a healthier alternative to refined sugar when consumed in moderation. It has been associated with potential benefits for heart health, including supporting healthy blood sugar and LDL cholesterol levels, though these findings are based on studies involving a healthy diet context. It may also aid in recovery from exercise and support the body’s natural defenses against stress and infections. Despite these benefits, Manuka honey is not suitable for infants under one year old, people with diabetes or blood-sugar control disorders, or those with a known honey allergy. It should be consumed in moderation due to its natural sugar content, which can raise blood sugar levels if overused. A higher UMF™ (Unique Manuka Factor) rating, typically 10+ or higher, indicates stronger antibacterial potency due to higher levels of methylglyoxal (MGO), dihydroxyacetone (DHA), and leptosperin. https://search.brave.com/search?q=manuka+honey+benefits&summary=1&conversation=e2c455d58326bf11d914f9.”
ClosedNicola asked 2 weeks ago • 
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Is Manuka honey preferable to use in general, or are there more beneficial forms of honey we can utilize?
ClosedNicola asked 2 weeks ago • 
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Is the key about honey utility, the plant source of pollen used by a particular hive? Would probing to get a rank-order preference from the divine perspective be rewarding?
ClosedNicola asked 2 weeks ago • 
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Was the book by G. Edward Griffen, World Without Cancer, a meaningful representation of Vitamin B17 (Laetrile) benefits as a valid treatment for cancer?
ClosedNicola asked 2 weeks ago • 
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Are apricot kernels a valid treatment for cancer?
ClosedNicola asked 2 weeks ago • 
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A review article shows little or no benefit of supplementing patients with vitamin D3 for bone fractures (T. Gatt, A. Grech, and H. Arshad. The effect of Vitamin D supplementation for bone healing in fracture patients: a systematic review. Adv. Orthopedics Volume 2023, Article ID 6236045). However, the supplement doses of vitamin D3 were either low, 800-2000 IU daily, or quite high loading doses orally or systemically of 100,000 to 300,000 IU. Was their negative assessment justified or were the studies flawed? Would taking a 5000 to 10,000 IU dose of vitamin D3 daily, give significant benefit for healing bone fractures?
ClosedNicola asked 2 months ago • 
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A systematic review of 416 medical journal articles affirmed a strong association between higher serum vitamin D levels and a lower risk of bladder, breast, colon, endometrial, esophageal, gallbladder, kidney, ovarian, pancreatic, rectal, stomach, and vulvar cancers, as well as Hodgkin’s and non-Hodgkin’s lymphomas. The review also uncovered lower risks of metastasis and mortality from cancer in patients with higher levels of vitamin D. While vitamin D levels of 20 ng/ml (50 nmol/L) were adequate for bone and muscle health, reduction of cancer risk and mortality required levels greater than 40 ng/ml (100 nmol/L) and fell further with levels above 50 ng/ml (125 nmol/L). The review cautioned that studies showing no benefit for those taking less than 5,000 IU per day might be misleading. [Wimalawansa SJ. Vitamin D’s impact on cancer incidence and mortality: a systematic review. Nutrients. 2025 Jul 16;17(14):2333. Doi: 10.3390/nu17142333.] Is this a fair summary of vitamin D benefits for limiting incidence and severity of cancer?
ClosedNicola asked 2 months ago • 
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You have told us that 5000 IU of vitamin D3 taken twice a day would be safe and helpful for many, many people. Is that enough to get serum levels in a useful range for cancer prevention?
ClosedNicola asked 2 months ago • 
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Studies have shown that vitamin D levels have an inverted U-shaped curve, where low levels (<29.7 nmol/L) result in shortened telomeres on DNA, a sign of aging, but so do high levels of vitamin D (>95.9 nmol/L). Population-based studies and randomized clinical trials have shown a U- or J-shaped curve and suggested an increased risk of adverse outcomes in those with the highest serum Vitamin D levels, including falls, fractures, and frailty. Most studies have reported a higher risk in those participants with serum levels above 100 nmol/L. Are the deleterious effects noted in these studies caused by elevated vitamin D? If so, your support for taking 5,000 to 10,000 IU of vitamin D3 daily seems risky. What is most important for us to know?
ClosedNicola asked 2 months ago • 
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A viewer asks: “What can you tell us about the benefits versus risk factors in taking the bone medication Evenity? Cost is high, but insurance can help. Can you tell us if it is highest and best to take this or if it would be better to continue LHP-DSMR healing requests without outside chemical interventions? Side effects with this drug are concerning.”
ClosedNicola asked 2 months ago • 
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You have said you would not recommend fenbendazole for treating or preventing cancer, but would support use of ivermectin and hydroxychloroquine. Dr. Andreas Kalcker promotes treatment of cancer using Chlorine Dioxide Solution to first reach a clinical redox plateau, then introduces albendazole/fenbendazole to impose mitotic stress, and then adds ivermectin to quiet excitatory signaling. In this scenario, the fenbendazole is used to block glucose handling by cancer cells to limit energy availability, and destabilize microtubules to hinder cell division. Is his theory sound? Is his timed sequence a more elegant way to utilize fenbendazole effectively to derive benefit?
ClosedNicola asked 5 months ago • 
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A practitioner asks: “An article [on the Internet] discusses the potential of fenbendazole, a common antiparasitic drug used in veterinary medicine, as a treatment for cancer. Fenbendazole (FBZ) has gained attention due to anecdotal reports suggesting it may have anticancer properties. FBZ may also enhance the efficacy of traditional cancer treatments like chemotherapy and radiation. FBZ though has no clinical literature as an anti-cancer treatment. How likely is it that FBZ could be a safe and effective anti-cancer treatment given that there are no treatment protocols, dosage, or side effect knowledge?”
ClosedNicola asked 5 months ago • 
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I am concerned about recommending people take 12 mg of ivermectin daily for 3 weeks (along with hydroxychloroquine). Was I over-influenced by having that interchange with [Name Withheld] about “his protocol” to believe that giving both compounds would effect a viral cleanout? Was this a lesson to me about being more thorough, knowing as I investigated the literature about appropriate doses of ivermectin I would see the pharmacokinetic data, revealing the inability of oral administration to reach antiviral concentrations? What is most important for me to know?
ClosedNicola asked 5 months ago • 
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