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A review article shows little or no benefit of supplementing patients with vitamin D3 for bone fractures (T. Gatt, A. Grech, and H. Arshad. The effect of Vitamin D supplementation for bone healing in fracture patients: a systematic review. Adv. Orthopedics Volume 2023, Article ID 6236045). However, the supplement doses of vitamin D3 were either low, 800-2000 IU daily, or quite high loading doses orally or systemically of 100,000 to 300,000 IU. Was their negative assessment justified or were the studies flawed? Would taking a 5000 to 10,000 IU dose of vitamin D3 daily, give significant benefit for healing bone fractures?
ClosedNicola asked 7 hours ago • 
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A systematic review of 416 medical journal articles affirmed a strong association between higher serum vitamin D levels and a lower risk of bladder, breast, colon, endometrial, esophageal, gallbladder, kidney, ovarian, pancreatic, rectal, stomach, and vulvar cancers, as well as Hodgkin’s and non-Hodgkin’s lymphomas. The review also uncovered lower risks of metastasis and mortality from cancer in patients with higher levels of vitamin D. While vitamin D levels of 20 ng/ml (50 nmol/L) were adequate for bone and muscle health, reduction of cancer risk and mortality required levels greater than 40 ng/ml (100 nmol/L) and fell further with levels above 50 ng/ml (125 nmol/L). The review cautioned that studies showing no benefit for those taking less than 5,000 IU per day might be misleading. [Wimalawansa SJ. Vitamin D’s impact on cancer incidence and mortality: a systematic review. Nutrients. 2025 Jul 16;17(14):2333. Doi: 10.3390/nu17142333.] Is this a fair summary of vitamin D benefits for limiting incidence and severity of cancer?
ClosedNicola asked 12 hours ago • 
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You have told us that 5000 IU of vitamin D3 taken twice a day would be safe and helpful for many, many people. Is that enough to get serum levels in a useful range for cancer prevention?
ClosedNicola asked 12 hours ago • 
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Studies have shown that vitamin D levels have an inverted U-shaped curve, where low levels (<29.7 nmol/L) result in shortened telomeres on DNA, a sign of aging, but so do high levels of vitamin D (>95.9 nmol/L). Population-based studies and randomized clinical trials have shown a U- or J-shaped curve and suggested an increased risk of adverse outcomes in those with the highest serum Vitamin D levels, including falls, fractures, and frailty. Most studies have reported a higher risk in those participants with serum levels above 100 nmol/L. Are the deleterious effects noted in these studies caused by elevated vitamin D? If so, your support for taking 5,000 to 10,000 IU of vitamin D3 daily seems risky. What is most important for us to know?
ClosedNicola asked 12 hours ago • 
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A viewer asks: “What can you tell us about the benefits versus risk factors in taking the bone medication Evenity? Cost is high, but insurance can help. Can you tell us if it is highest and best to take this or if it would be better to continue LHP-DSMR healing requests without outside chemical interventions? Side effects with this drug are concerning.”
ClosedNicola asked 2 weeks ago • 
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You have said you would not recommend fenbendazole for treating or preventing cancer, but would support use of ivermectin and hydroxychloroquine. Dr. Andreas Kalcker promotes treatment of cancer using Chlorine Dioxide Solution to first reach a clinical redox plateau, then introduces albendazole/fenbendazole to impose mitotic stress, and then adds ivermectin to quiet excitatory signaling. In this scenario, the fenbendazole is used to block glucose handling by cancer cells to limit energy availability, and destabilize microtubules to hinder cell division. Is his theory sound? Is his timed sequence a more elegant way to utilize fenbendazole effectively to derive benefit?
ClosedNicola asked 2 months ago • 
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A practitioner asks: “An article [on the Internet] discusses the potential of fenbendazole, a common antiparasitic drug used in veterinary medicine, as a treatment for cancer. Fenbendazole (FBZ) has gained attention due to anecdotal reports suggesting it may have anticancer properties. FBZ may also enhance the efficacy of traditional cancer treatments like chemotherapy and radiation. FBZ though has no clinical literature as an anti-cancer treatment. How likely is it that FBZ could be a safe and effective anti-cancer treatment given that there are no treatment protocols, dosage, or side effect knowledge?”
ClosedNicola asked 2 months ago • 
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I am concerned about recommending people take 12 mg of ivermectin daily for 3 weeks (along with hydroxychloroquine). Was I over-influenced by having that interchange with [Name Withheld] about “his protocol” to believe that giving both compounds would effect a viral cleanout? Was this a lesson to me about being more thorough, knowing as I investigated the literature about appropriate doses of ivermectin I would see the pharmacokinetic data, revealing the inability of oral administration to reach antiviral concentrations? What is most important for me to know?
ClosedNicola asked 2 months ago • 
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Recommending use of ivermectin in a way that is not even scientifically supportable seems like a big risk, even if you say it will work. What am I missing? How can high protein binding not be a hindrance to achieving a therapeutic exposure to free drug? Is there a scientific phenomenon here not yet scientifically understood or appreciated, at least not be me? Can you give us a tutorial to explain your continued endorsement and value of ivermectin, in addition to hydroxychloroquine which has demonstrated in vivo efficacy as an antiviral?
ClosedNicola asked 2 months ago • 
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In a paper on the pharmacokinetics of ivermectin, they report that even at a very high dose, free plasma levels never get close to the concentration needed, shown by in vitro studies, to demonstrate antiviral activity because ivermectin is 93% bound to plasma proteins. Yet, you have reassured us that taking an oral dose of 12 mg daily for 3 weeks would be effective in many cases for getting a profound, if not total, eradication of susceptible chronic viruses. Can you explain how that is possible?
ClosedNicola asked 2 months ago • 
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Does cod liver oil contain significant antiviral activity, enough to diminish viral disease symptoms or even cure chronic viral maladies?
ClosedNicola asked 3 months ago • 
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A viewer asks: “Various sources recommend supplementing the diet with 3000 mg daily of fish oil, but it’s not specifically one of the Creator recommendations from what I can see on the database. I have Kirkland Fish Oil Blend from Costco, with Alaskan Salmon Oil, and includes 400 capsules of one thousand milligrams. Each capsule contains EPA of 180 mg, AEP/DHA of 120 mg, and ADH. The vendor claims this is all from wild fish, not farmed. On the other hand, many caution against toxins that fish are subjected to from the oceans. I have also been consuming more fish, mostly salmon and trout. Is this more risk than good for the human body? What can Creator tell us about these fish sources of nutrition?”
ClosedNicola asked 3 months ago • 
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I found a publication showing squalene has anticancer effects on renal cell carcinoma cells. Does this support use of squalene by my client who has a renal lesion on his scan? Will it be especially well-suited for treating his condition?
ClosedNicola asked 3 months ago • 
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A study was just reported that ivermectin, in a nanoparticle formulation for helping to cross the blood-brain barrier, was highly effective in shrinking brain tumors in rats by 70% after giving a tiny daily dose for 10 days. Because of poor drug delivery to the brain without a special formulation, does this mean that ivermectin will not be effective in treating dementia, despite its antiviral activity?
ClosedNicola asked 3 months ago • 
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Does Shark Liver Oil have direct anticancer activity against malignant cells or tumor growth?
ClosedNicola asked 3 months ago • 
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