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Amyotrophic lateral sclerosis is considered a genetic disorder for those with familial ALS. While the causes of sporadic ALS and ALS/dementia have been unknown, a recent study published in Nature showed that there is a defect in a protein degradation pathway involving ubiquilin2, which normally clears misfolded proteins in all three forms of ALS. Is this the true underlying cause of all ALS or does expression of the disease actually require a viral infection to be present as well?
ClosedNicola asked 2 years ago • 
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Are gallstones formed in response to a viral infection? If so, in what percent of cases?
ClosedNicola asked 2 years ago • 
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Are kidney stones formed in response to a viral infection? If so, in what percent of cases?
ClosedNicola asked 2 years ago • 
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Is a chronic viral infection the underlying cause of all four main types of kidney stones: calcium, uric acid, struvite, and cystine?
ClosedNicola asked 2 years ago • 
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Is melanoma viral in origin, and if so, in what percent of cases?
ClosedNicola asked 2 years ago • 
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If melanoma is caused by a virus, does successful eradication of the disease through surgery happen because the virus is confined to the tissue in or immediately adjacent to the actual malignant lesions? Or is there usually a remaining level of virus in the body, but suppressed enough by the immune system to not become a problem in most cases?
ClosedNicola asked 2 years ago • 
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What percent of intestinal polyps are due to a viral presence in the tissues?
ClosedNicola asked 2 years ago • 
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What percent of osteoporosis cases, if any, are caused by a chronic viral infection?
ClosedNicola asked 2 years ago • 
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Dupuytren’s disease is thought to have a genetic association as it runs in families. Is presence of a chronic virus also essential for development of symptoms?
ClosedNicola asked 2 years ago • 
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Are flashbacks the experiencing of memories residing in cordings that are rumbling in order to provide reminders or warnings?
ClosedNicola asked 2 years ago • 
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What percent of people have gastrointestinal reflux (GERD) because of a chronic viral infection?
ClosedNicola asked 2 years ago • 
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In what percent of esophageal cancer patients is the malignancy caused by chronic viral infection?
ClosedNicola asked 2 years ago • 
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Is there a difference in the percent of viral causation of esophageal squamous cell carcinoma vs. adenocarcinoma?
ClosedNicola asked 2 years ago • 
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What percent of cases of esophageal achalasia are caused by chronic viral infection?
ClosedNicola asked 2 years ago • 
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What percent of cases of primary (essential) hypertension are caused by chronic viral infection?
ClosedNicola asked 2 years ago • 
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