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A review article shows little or no benefit of supplementing patients with vitamin D3 for bone fractures (T. Gatt, A. Grech, and H. Arshad. The effect of Vitamin D supplementation for bone healing in fracture patients: a systematic review. Adv. Orthopedics Volume 2023, Article ID 6236045). However, the supplement doses of vitamin D3 were either low, 800-2000 IU daily, or quite high loading doses orally or systemically of 100,000 to 300,000 IU. Was their negative assessment justified or were the studies flawed? Would taking a 5000 to 10,000 IU dose of vitamin D3 daily, give significant benefit for healing bone fractures?
ClosedNicola asked 4 days ago • 
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A systematic review of 416 medical journal articles affirmed a strong association between higher serum vitamin D levels and a lower risk of bladder, breast, colon, endometrial, esophageal, gallbladder, kidney, ovarian, pancreatic, rectal, stomach, and vulvar cancers, as well as Hodgkin’s and non-Hodgkin’s lymphomas. The review also uncovered lower risks of metastasis and mortality from cancer in patients with higher levels of vitamin D. While vitamin D levels of 20 ng/ml (50 nmol/L) were adequate for bone and muscle health, reduction of cancer risk and mortality required levels greater than 40 ng/ml (100 nmol/L) and fell further with levels above 50 ng/ml (125 nmol/L). The review cautioned that studies showing no benefit for those taking less than 5,000 IU per day might be misleading. [Wimalawansa SJ. Vitamin D’s impact on cancer incidence and mortality: a systematic review. Nutrients. 2025 Jul 16;17(14):2333. Doi: 10.3390/nu17142333.] Is this a fair summary of vitamin D benefits for limiting incidence and severity of cancer?
ClosedNicola asked 4 days ago • 
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You have told us that 5000 IU of vitamin D3 taken twice a day would be safe and helpful for many, many people. Is that enough to get serum levels in a useful range for cancer prevention?
ClosedNicola asked 4 days ago • 
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Studies have shown that vitamin D levels have an inverted U-shaped curve, where low levels (<29.7 nmol/L) result in shortened telomeres on DNA, a sign of aging, but so do high levels of vitamin D (>95.9 nmol/L). Population-based studies and randomized clinical trials have shown a U- or J-shaped curve and suggested an increased risk of adverse outcomes in those with the highest serum Vitamin D levels, including falls, fractures, and frailty. Most studies have reported a higher risk in those participants with serum levels above 100 nmol/L. Are the deleterious effects noted in these studies caused by elevated vitamin D? If so, your support for taking 5,000 to 10,000 IU of vitamin D3 daily seems risky. What is most important for us to know?
ClosedNicola asked 4 days ago • 
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A viewer asks: “What can you tell us about the benefits versus risk factors in taking the bone medication Evenity? Cost is high, but insurance can help. Can you tell us if it is highest and best to take this or if it would be better to continue LHP-DSMR healing requests without outside chemical interventions? Side effects with this drug are concerning.”
ClosedNicola asked 2 weeks ago • 
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The trial to assess chelation therapy 2 (TACT2) on cardiovascular outcomes in patients with diabetes and a prior myocardial infarction (MI) was reported in September, 2024. While there was a significant reduction in circulating heavy metals following months of weekly intravenous EDTA infusions, there was not a significant reduction in cardiovascular events or mortality. You told us previously that EDTA therapy was actually beneficial, as the first TACT study showed, but that the interlopers were suppressing beneficial clinical data. Is that the reason for the failed confirmation with the TACT2 follow-up?
ClosedNicola asked 10 months ago • 
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A viewer asks: “Is Mirror Life Microbe research an interloper technology existing within their own societies or is this directed at humans only (as so many other things)?” What is Creator’s perspective?
ClosedNicola asked 10 months ago • 
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A viewer asks: “Seasilver was a supplement containing the herb pau d’arco, cranberry, and aloe. It got a lot of fanfare back in the late 90s and early 2000s. It was run out of business by the FTC and fined $120 million. They ceased doing business in 2006. Was this an ‘honest’ product being sold for its genuine health benefits? Or a scam? Or was it a good product whose benefits were exaggerated intentionally, with awareness, or unintentionally? Did they legitimately run afoul of the FDA and FTC, or were they targeted by overzealous enforcement, reading ‘too much’ into the laws and regulations governing supplements? Who are the bad guys here and who are the good guys, or were they both breaking and bending the rules of ‘fair play?'” What can Creator tell us?
ClosedNicola asked 12 months ago • 
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He asks: “Did this constitute an interloper backlash of the manufacturers and sellers of this Seasilver product? Is this an object lesson we should be mindful of?” What can Creator tell us?
ClosedNicola asked 12 months ago • 
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You clarified that Vitamin D levels of 40 to 60 ng/mL are important for healthy well-being, but not specifically how important this vitamin is for the recommended Antiviral Regimen to be effective. What is most important for us to know?
ClosedNicola asked 12 months ago • 
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A viewer asks: “Is the efficacy of Creator’s antivirals affected by a person’s vitamin D levels? A recent research paper, ‘Vitamin D: A key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variants,’ suggests all viral infections are more effectively treated when patients have vitamin D levels between 30-60ng/mL. In 2011, the Endocrine Society urged that: ‘to guarantee sufficiency, we recommend between 40 and 60 ng/mL for both children and adults.'” What can we tell him?
ClosedNicola asked 12 months ago • 
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He asks: “Will Creator’s Antiviral Regimen efficacy improve significantly at vitamin D recommended levels of 40 to 60 ng/mL? Should vitamin K2 also be taken to boost absorption of vitamin D?” What can we tell him?
ClosedNicola asked 12 months ago • 
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The Endocrine Society updated their guidelines for 2024 to advise against routine vitamin D screening and routine supplementation for certain populations, including non-pregnant adults aged 19 to 74. The Society cited lack of definitive clinical data to support the benefits, and this reverses previous guidelines that recommended supplementation among all age groups. Is this a good policy, and if vitamin D supplementation is truly justified, why is there a lack of conclusive scientific evidence?
ClosedNicola asked 1 year ago • 
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A viewer asks: “Professor Angus Dalgleish, the chair of oncology at St George’s, University of London, has conducted research and clinical work on the role of vitamin D in cancer, particularly focusing on its potential benefits for cancer patients. He prescribes very high doses of vitamin D to some cancer patients to raise their blood levels significantly to boost vitamin D levels to around 100 nmol/L. How beneficial, as part of a comprehensive cancer treatment approach, are such doses likely to be and how variable in outcomes for different patient demographics?” What can Creator tell us?
ClosedNicola asked 1 year ago • 
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A viewer asks: “Calcifediol is the precursor for calcitriol, the active form of vitamin D synthesized in the liver. Is Calcifediol likely to be a beneficial treatment (orally administered), that acts faster than antibiotics, for people acutely infected with a bacterial or viral infection to boost the efficiency of the immune system?” What can Creator tell us?
ClosedNicola asked 1 year ago • 
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