DWQA Questions › Tag: human wellbeing
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A viewer asks: “Being aware of Creator’s previous answers on Vitamin D3 supplementation I was shocked to discover a paper from 2014 “A Statistical Error in the Estimation of the Recommended Dietary Allowance for Vitamin D”. The paper claims that the Recommended Daily Allowance advocated by the Institute of Medicine for Vitamin D was incorrectly calculated! In fact, analyzing the data correctly, nearly 9000 IUs per day are required to achieve target levels (600 IU per day is the USA recommended level). I was struck by how closely the 9000 IU figure matched Creator’s “daily doses of 5,000 to 10,000 IU vitamin D3 will rarely be harmful.” What is Creator’s perspective on this “miscalculation” coming to light?”
ClosedNicola asked 1 week ago • 
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A British group reported recently that administration of vitamin D2, which is converted to vitamin D3 by the body, may be disadvantageous. A review of random controlled trials showed that taking vitamin D2 can lead to a decrease in vitamin D3 levels, the more active form generated by sunlight exposure. The research indicates that D2 supplementation may not only be less effective, but can also lead to lower concentrations of D3 in the circulation. [Emily I G Brown, et al. Effect of Vitamin D2 Supplementation on 25-Hydroxyvitamin D3 Status: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutr Rev, 2025 Sep 18:nuaf166.doi: 10.1093/nutrit/nuaf166]. Is this an accurate and meaningful assessment? What is most important for us to know?
ClosedNicola asked 1 week ago • 
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Is Vibration Therapy using the Power Plate Personal Machine a significant benefit for helping to counter a number of aging-related impairments causing a decline in function, or is it being over-hyped?
ClosedNicola asked 1 week ago • 
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Is Vibration Therapy using the Power Plate Personal Machine of particular value in helping to reverse or prevent problems in the elderly, from cognitive decline, obesity, loss of muscle mass, hypertension, and bone loss, to reducing muscle aches and pains, stiffness, joint pains, and beneficial hormone increases?
ClosedNicola asked 1 week ago • 
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A review article shows little or no benefit of supplementing patients with vitamin D3 for bone fractures (T. Gatt, A. Grech, and H. Arshad. The effect of Vitamin D supplementation for bone healing in fracture patients: a systematic review. Adv. Orthopedics Volume 2023, Article ID 6236045). However, the supplement doses of vitamin D3 were either low, 800-2000 IU daily, or quite high loading doses orally or systemically of 100,000 to 300,000 IU. Was their negative assessment justified or were the studies flawed? Would taking a 5000 to 10,000 IU dose of vitamin D3 daily, give significant benefit for healing bone fractures?
ClosedNicola asked 2 months ago • 
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A systematic review of 416 medical journal articles affirmed a strong association between higher serum vitamin D levels and a lower risk of bladder, breast, colon, endometrial, esophageal, gallbladder, kidney, ovarian, pancreatic, rectal, stomach, and vulvar cancers, as well as Hodgkin’s and non-Hodgkin’s lymphomas. The review also uncovered lower risks of metastasis and mortality from cancer in patients with higher levels of vitamin D. While vitamin D levels of 20 ng/ml (50 nmol/L) were adequate for bone and muscle health, reduction of cancer risk and mortality required levels greater than 40 ng/ml (100 nmol/L) and fell further with levels above 50 ng/ml (125 nmol/L). The review cautioned that studies showing no benefit for those taking less than 5,000 IU per day might be misleading. [Wimalawansa SJ. Vitamin D’s impact on cancer incidence and mortality: a systematic review. Nutrients. 2025 Jul 16;17(14):2333. Doi: 10.3390/nu17142333.] Is this a fair summary of vitamin D benefits for limiting incidence and severity of cancer?
ClosedNicola asked 2 months ago • 
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You have told us that 5000 IU of vitamin D3 taken twice a day would be safe and helpful for many, many people. Is that enough to get serum levels in a useful range for cancer prevention?
ClosedNicola asked 2 months ago • 
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Studies have shown that vitamin D levels have an inverted U-shaped curve, where low levels (<29.7 nmol/L) result in shortened telomeres on DNA, a sign of aging, but so do high levels of vitamin D (>95.9 nmol/L). Population-based studies and randomized clinical trials have shown a U- or J-shaped curve and suggested an increased risk of adverse outcomes in those with the highest serum Vitamin D levels, including falls, fractures, and frailty. Most studies have reported a higher risk in those participants with serum levels above 100 nmol/L. Are the deleterious effects noted in these studies caused by elevated vitamin D? If so, your support for taking 5,000 to 10,000 IU of vitamin D3 daily seems risky. What is most important for us to know?
ClosedNicola asked 2 months ago • 
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How effective is the Primal Force supplement, Telo X Nano, for adding to longevity?
ClosedNicola asked 2 months ago • 
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A viewer asks: “Would I benefit from taking Telo X Nano? I am taking nearly all the ingredients except for arginine alpha ketoglutarate and carnosine, although not in the “nano” form promoted by Primal Force as achieving better bioavailability.”
ClosedNicola asked 2 months ago • 
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Given the recent paper showing a good anticancer effect of both grape seed extract and vitamin C in a mouse model of solid Ehrlich carcinoma, would either or both be a safe and effective addition to our Antiviral Regimen?
ClosedNicola asked 2 months ago • 
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You have told us that taking 2,000 IU of vitamin D3 is safe and very helpful, because the Recommended Daily Allowance, as with many essential nutrients, is way too low. I have seen doctor recommendations that say when health issues are present it is meaningful and safe to take as much as 10,000 IU of vitamin D3. I have been taking 5,000 IU twice a day. Is that safe and useful for me and others? What is most important for us to know?
ClosedNicola asked 2 months ago • 
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A viewer asks: “What can you tell us about the benefits versus risk factors in taking the bone medication Evenity? Cost is high, but insurance can help. Can you tell us if it is highest and best to take this or if it would be better to continue LHP-DSMR healing requests without outside chemical interventions? Side effects with this drug are concerning.”
ClosedNicola asked 2 months ago • 
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Is the “Brain Song” being advertised as able to enhance memory by stimulating Brain Derived Neurotrophic Factor after 17 minute listening sessions, truly effective and superior to other, routine, cognitive exercises, such as listening to music, playing an instrument, tackling demanding creative decision-making tasks, etc?
ClosedNicola asked 2 months ago • 
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A viewer asks: “Recently I started taking a sulforaphane supplement by the name of Broq and within two weeks I noticed surprising benefits. My energy levels have been slightly elevated along with my mood, my hair shedding has returned to normal levels and my complexion has improved. Does sulforaphane have anti-viral properties or is the sulforaphane working somewhere downstream to mitigate symptoms and damage caused by chronic viral infections? Can sulforaphane provide broad benefits to a majority of people by protecting against various forms of cancer, prevent cardiovascular disease, reduce symptoms of autism, and slow aging or are these claims exaggerations?”
ClosedNicola asked 4 months ago • 
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