DWQA Questions › Tag: inflammation
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Was the research, including the clinical data, for the paper we asked you about, “Acute inflammatory response via neutrophil activation protects against development of chronic pain,” valid and not corrupted by the interlopers to malign seemingly useful common painkillers? Given your warnings that clinical research cannot always be trusted, we just want to be sure. What is most important for us to know?
ClosedNicola asked 6 months ago • 
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The phenomena seem quite striking which are reported in the paper, “Acute inflammatory response via neutrophil activation protects against development of chronic pain,” by Marc Parisien et al. Sci Transl Med. 2022 May 11; 14(644). These authors showed in animal models that painkillers like corticosteroids and NSAIDs, but not analgesics like morphine or lidocaine which lack anti-inflammatory effects, end up prolonging pain, because without neutrophil activation being allowed to happen as part of an immune response, acute pain may become chronic. A clinical study confirmed that among patients whose lower back pain had become chronic, it was exclusively those who had been treated with NSAIDS who went on to develop neuropathy. Was this a valid study with broad implications about the unexpected downside of anti-inflammatory medication for moderating pain? What is Creator’s perspective?
ClosedNicola asked 6 months ago • 
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I shudder when I consider I spent years striving to develop inhibitors of neutrophil activation as therapeutics for autoimmune disease. Was that not only misguided, but a sinister consequence of interloper manipulation to encourage the field of immunopharmacology, knowing it could make things worse? What can Creator tell us about the medical implications for using anti-inflammatories?
ClosedNicola asked 6 months ago • 
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What percent of proctitis cases are viral in origin?
ClosedNicola asked 9 months ago • 
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A viewer asks: “Is Clic Gourmet Rose Water a helpful healing adjunct for issues such as inflammation and infection? My girlfriend’s mother had a wart or cyst on her foot and was scheduled for surgical removal, but was applying rose water and it disappeared. The doctor was amazed. I am now trying it on inflammation in my wrist that is lingering after a fall on March 30th.” What can Creator tell us?
ClosedNicola asked 9 months ago • 
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I found a publication showing squalene has anticancer effects on renal cell carcinoma cells. Does this support use of squalene by my client who has a renal lesion on his scan? Will it be especially well-suited for treating his condition?
ClosedNicola asked 9 months ago • 
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A viewer asks: “I wanted to follow up with Creator on my gastroenterologist diagnosis. Also, my migraine management I just started 3 weeks ago. I would greatly appreciate feedback on these to see if I’m going in the right direction to healing and pain management moving forward. First, with the gastroenterologist, the doctor was very detail-oriented which I really appreciated and took time to explain my situation; he said I have Proctitis and prescribed Salofalk 1000mg insert x2. Will this fully resolve my issue and approximately how long will it take if so?” What can we tell him?
ClosedNicola asked 9 months ago • 
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He asks: “What causes the Proctitis to begin with and how can I prevent it in the future?” What can we tell him?
ClosedNicola asked 9 months ago • 
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He asks: “For the migraines, my doctor prescribed Vermapal 80mg; I’m to take it 3x daily, morning, midday, 3pm, and 9pm. I think it’s working. However, because they last only about 4 hours each, my night sleep is not covered, so during the day I’m fine but I’ll wake up some days and have a small headache that will become a full-blown migraine by the end of the day. Will this be safe to use long term?” What can we tell him?
ClosedNicola asked 9 months ago • 
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He asks: “If safe, will a slow-release 24-hour version of Vermapal from the same type work for me in controlling the migraines day and night?” What can we tell him?
ClosedNicola asked 9 months ago • 
239 views0 answers0 votes
He asks: “I feel I’m finally hopeful I’m making headway with both of these health issues. I understand and appreciate the LHPs, DSMRs, and HMRs that I have done and continue to do but I realize, as you have said, the actual pain, etc., one copes with is the last thing that will be removed, and that may not come for most of us in the lifetime if I remember correctly. So can this be a stopgap solution?” What can we tell him?
ClosedNicola asked 9 months ago • 
185 views0 answers0 votes
Is the Austin Herbal Sciences supplement, FleXion, both safe and effective for managing joint pain as well as restoring joint health and function? How does it rank compared to the many other supplements promising painful joint relief?
ClosedNicola asked 1 year ago • 
281 views0 answers-1 votes
Is the local delivery by FleXion of its ingredients to affected joints through topical application a particular advantage compared to other approaches for helping joint symptoms and improving function?
ClosedNicola asked 1 year ago • 
318 views0 answers0 votes
Conolidine is one of 64 powerful indole alkaloids found inside the ancient plant Tabernaemontana divaricata or more commonly known as “crepe jasmine.” Historically, this plant has been used since ancient times as a powerful pain reliever and is a staple in Chinese, Ayurvedic, and Thai medicine. Studies have confirmed that conolidine is nearly as potent as morphine in alleviating inflammatory and acute pain but is non-addicting, with few, if any, side effects. Is the indole alkaloid plant extract from GDR Labs modified to greatly increase oral bioavailability of conolidine as they claim?
ClosedNicola asked 2 years ago • 
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Does the mixture of many indole alkaloids extracted together from the plant of origin confer any benefits compared to purified conolidine alone? Is the extract effective and safe for a wide variety of painful conditions as they claim?
ClosedNicola asked 2 years ago • 
383 views0 answers0 votes
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