DWQA Questions › Tag: mortalityFilter:AllOpenResolvedClosedUnansweredSort byViewsAnswersVotesWhat about using the Moderna COVID-19 vaccine and its safety profile?ClosedNicola asked 5 years ago • Coronavirus COVID-19545 views0 answers0 votesThe Lancet just published a 96,000-patient registry analysis of multinational clinical data from hospitalized patients with COVID-19 comparing outcomes of four non-randomized treatment groups compared to controls: Chloroquine alone, chloroquine with a macrolide, hydroxychloroquine alone, or hydroxychloroquine with a macrolide. The main endpoints were in-hospital mortality and sustained ventricular tachycardia or ventricular fibrillation. There was no confirmed benefit of any treatment, and each of these drug regimens were associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias. Despite the fact this was not a careful randomized trial, it has been widely touted by the press, condemning the use of hydroxychloroquine as not only useless but dangerous for COVID-19 therapy. What is your interpretation of these data?ClosedNicola asked 5 years ago • Coronavirus COVID-19440 views0 answers0 votesNew information has emerged that “COVID-19 causes prolonged and progressive hypoxia (starving your body of oxygen) by binding to the heme groups in hemoglobin in your red blood cells. People are simply desaturating (losing O2 in their blood), and that’s what eventually leads to organ failures that kill them, not any form of Acute Respiratory Distress Syndrome (ARDS) or pneumonia. All the damage to the lungs you see in CT scans is from the release of oxidative iron from the hemes, this overwhelms the natural defenses against pulmonary oxidative stress and causes that nice, always-bilateral ground glass opacity in the lungs. Patients returning for re-hospitalization days or weeks after recovery suffering from apparent delayed post-hypoxic leukoencephalopathy strengthen the notion COVID-19 patients are suffering from hypoxia despite no signs of respiratory “tire out” or fatigue.” Is this true and a major factor in the morbidity and mortality?ClosedNicola asked 5 years ago • Coronavirus COVID-19697 views0 answers0 votesWill the release of reactive iron ions from hemoglobin by attaching coronavirus particles result in severe oxidative damage to tissues in addition to rendering hemoglobin unable to transport oxygen efficiently?ClosedNicola asked 6 years ago • Coronavirus COVID-19567 views0 answers0 votes
Nicola