DWQA Questions › Tag: vitamin D3
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A viewer asks: “Being aware of Creator’s previous answers on Vitamin D3 supplementation I was shocked to discover a paper from 2014 “A Statistical Error in the Estimation of the Recommended Dietary Allowance for Vitamin D”. The paper claims that the Recommended Daily Allowance advocated by the Institute of Medicine for Vitamin D was incorrectly calculated! In fact, analyzing the data correctly, nearly 9000 IUs per day are required to achieve target levels (600 IU per day is the USA recommended level). I was struck by how closely the 9000 IU figure matched Creator’s “daily doses of 5,000 to 10,000 IU vitamin D3 will rarely be harmful.” What is Creator’s perspective on this “miscalculation” coming to light?”
ClosedNicola asked 10 hours ago • 
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A British group reported recently that administration of vitamin D2, which is converted to vitamin D3 by the body, may be disadvantageous. A review of random controlled trials showed that taking vitamin D2 can lead to a decrease in vitamin D3 levels, the more active form generated by sunlight exposure. The research indicates that D2 supplementation may not only be less effective, but can also lead to lower concentrations of D3 in the circulation. [Emily I G Brown, et al. Effect of Vitamin D2 Supplementation on 25-Hydroxyvitamin D3 Status: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutr Rev, 2025 Sep 18:nuaf166.doi: 10.1093/nutrit/nuaf166]. Is this an accurate and meaningful assessment? What is most important for us to know?
ClosedNicola asked 10 hours ago • 
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A review article shows little or no benefit of supplementing patients with vitamin D3 for bone fractures (T. Gatt, A. Grech, and H. Arshad. The effect of Vitamin D supplementation for bone healing in fracture patients: a systematic review. Adv. Orthopedics Volume 2023, Article ID 6236045). However, the supplement doses of vitamin D3 were either low, 800-2000 IU daily, or quite high loading doses orally or systemically of 100,000 to 300,000 IU. Was their negative assessment justified or were the studies flawed? Would taking a 5000 to 10,000 IU dose of vitamin D3 daily, give significant benefit for healing bone fractures?
ClosedNicola asked 2 months ago • 
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Green Valley Naturals is offering a supplement called Bone and Muscle Defense they claim both strengthens bones as well as rebuilding muscle mass. It contains Vitamin D3, calcium, magnesium, calcium -hydroxy--methylbutyrate, L-carnitine, Cuscuta chinensis, Cnidium monnieri, and vitamin K2 as menaquinone-7. Is this safe, effective, and of significant value for helping those with aging-related bone, joint, and muscle loss issues?
ClosedNicola asked 2 months ago • 
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You have said that the Advanced Muscle Plus supplement from Advanced Bionutritionals can be used along with their Advanced Amino Formula to “…be a powerful one-two knockout combination that will be quite effective for many wanting to regain lost muscle mass and strength.” How would you rank this duo with taking the Bone and Muscle Defense supplement from Green Valley Naturals?
ClosedNicola asked 2 months ago • 
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Would there be a significant benefit to taking all three supplements [Advanced Muscle Plus, Advanced Amino Formula, and Bone and Muscle Defense] for repairing low bone density, damaged joints, and lost muscle mass?
ClosedNicola asked 2 months ago • 
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Would taking the best combination [of Advanced Muscle Plus, Advanced Amino Formula, and Bone and Muscle Defense] help speed up repair of my painful right shoulder and right hip?
ClosedNicola asked 2 months ago • 
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You have told us that taking 2,000 IU of vitamin D3 is safe and very helpful, because the Recommended Daily Allowance, as with many essential nutrients, is way too low. I have seen doctor recommendations that say when health issues are present it is meaningful and safe to take as much as 10,000 IU of vitamin D3. I have been taking 5,000 IU twice a day. Is that safe and useful for me and others? What is most important for us to know?
ClosedNicola asked 2 months ago • 
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A viewer asks: “I don’t see anything on the Creator database about creatine, but it has a lot of press, if you will, on YouTube and elsewhere from prominent people, such as Dr. Paul Saladino, longevity researcher Rhonda Patrick, and Joe Rogan. It’s supposed to be extremely good for strength and muscle recovery, as well as cognitive benefits, and earlier recommended daily amounts should be tripled. Back in the 90s, I recall using creatine monohydrate and I see now that research indicates 60% better uptake with creatine hydroxychloride. Have you looked into this area?” What is Creator’s perspective about the relative benefit of creatine supplementation for building muscle mass? How does it compare to using Advanced Muscle Plus and Advanced Amino Powder?
ClosedNicola asked 4 months ago • 
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A viewer asks: “How effective is creatine supplementation for cognitive performance compared to the memory-enhancing FocusIQ supplement from PrimalForce.net or the Advanced Memory Formula from Advanced Bionutritionals?” What can we tell him?
ClosedNicola asked 4 months ago • 
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The supplement Advanced Muscle Plus is said to work, in part, through modulating the mTOR pathway. The latter is involved in many bodily functions, including both favorable and possibly unfavorable effects on cardiovascular function. Is there a likelihood of the Advanced Muscle Plus supplement causing adverse effects, or will it be safe to use for building new muscle mass?
ClosedNicola asked 4 months ago • 
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Am I taking too much vitamin D3? Dr. Sears recommends 2000 IU daily. I am taking two 5000 IU gelcaps. Is it better to take half at noon and half at night, or is taking two together wasteful?
ClosedNicola asked 4 months ago • 
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Is the vitamin D3 I am taking going to waste unless I take a more absorbable form of zinc, like zinc acetate?
ClosedNicola asked 4 months ago • 
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I saw a paper raising a safety issue about involvement of mTOR with high-protein diets as increasing risk for atherosclerosis. Is there a possible safety hazard in the use of Advanced Muscle Plus along with Advanced Amino Formula?
ClosedNicola asked 4 months ago • 
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You have said that the Advanced Muscle Plus supplement from Advanced Bionutritionals is superior to their Advanced Amino Formula (or the Advanced Amino Powder version) for addressing loss of muscle mass. Would using one of the latter, along with Advanced Muscle Plus achieve a greater or quicker benefit that would justify the added expense?
ClosedNicola asked 4 months ago • 
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