DWQA Questions › Tag: hydroxychloroquineFilter:AllOpenResolvedClosedUnansweredSort byViewsAnswersVotesA study just completed in the U.S. and Canada of 821 health care workers exposed to people with COVID-19 infections failed to show a statistically significant benefit of hydroxychloroquine in preventing infections (11.8% with hydroxychloroquine versus 14.3% of placebo group became ill). There was also no significant lessening of disease severity once they became symptomatic. How can the data be explained in view of your support for hydroxychloroquine use?ClosedNicola asked 3 years ago • Coronavirus COVID-19254 views0 answers0 votesThe Lancet just published a 96,000-patient registry analysis of multinational clinical data from hospitalized patients with COVID-19 comparing outcomes of four non-randomized treatment groups compared to controls: Chloroquine alone, chloroquine with a macrolide, hydroxychloroquine alone, or hydroxychloroquine with a macrolide. The main endpoints were in-hospital mortality and sustained ventricular tachycardia or ventricular fibrillation. There was no confirmed benefit of any treatment, and each of these drug regimens were associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias. Despite the fact this was not a careful randomized trial, it has been widely touted by the press, condemning the use of hydroxychloroquine as not only useless but dangerous for COVID-19 therapy. What is your interpretation of these data?ClosedNicola asked 3 years ago • Coronavirus COVID-19224 views0 answers0 votesThe New England Journal of Medicine just published a non-randomized study of hydroxychloroquine coupled with azithromycin in patients with moderate to severe COVID-19 infections, showing no benefit compared to a control group, using intubation or death as endpoints. Can you comment on the prospects for this therapy, in light of this study and your prior endorsement of this treatment?ClosedNicola asked 3 years ago • Coronavirus COVID-19286 views0 answers0 votesA viewer asks: “Is hydroxychloroquine also known as quinine that was used for years in the past?”ClosedNicola asked 3 years ago • Coronavirus COVID-19254 views0 answers0 votesA viewer asks: “Does hydroxychloroquine have advantages over quinine as an antiviral in treating coronavirus infections, and a better or worse side effect profile?”ClosedNicola asked 3 years ago • Coronavirus COVID-19263 views0 answers0 votesWhat is the reason that the mainstream media continues to disparage the many recommendations to treat coronavirus infection with hydroxychloroquine, perhaps in combination with other drugs? Is this an orchestration?ClosedNicola asked 4 years ago • Coronavirus COVID-19816 views0 answers0 votesDoes hydroxychloroquine block the ability of coronavirus to interfere with hemoglobin function and preserve its oxygen-carrying capacity in a way that parallels its ability to protect hemoglobin from malaria parasites?ClosedNicola asked 4 years ago • Coronavirus COVID-19504 views0 answers0 votesA viewer asks: “Does hydroxychloroquine have advantages over quinine as an antiviral in treating coronavirus infections, and a better or worse side effect profile?”ClosedNicola asked 4 years ago • Coronavirus COVID-19380 views0 answers0 votesIs the recent small study combining azithromycin with hydroxychloroquine in treating coronavirus COVID-19 accurate in reflecting significant clinical benefit due to both anti-inflammatory and antiviral replication activities? Will this be a valuable adjunct in reducing the impact of the pandemic?ClosedNicola asked 4 years ago • Coronavirus COVID-19396 views0 answers0 votes