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The Pfizer and Moderna COVID-19 vaccines did not impact overall mortality, a reanalysis of clinical trial data found. The two vaccines, both based on messenger RNA (mRNA) technology, protected against deaths from COVID-19 but that effect was offset by vaccinated trial participants being more likely to die from cardiovascular problems, Christine Stabell Benn, a health professor at the University of Southern Denmark, and other researchers reported in April in the journal, Cell. On the other hand, vaccines that utilized adenoviruses, such as the Johnson & Johnson vaccine, had a favorable impact on both COVID-19 mortality and overall mortality, according to the reanalysis. The research analyzed data from randomized clinical trials (RCTs) reported by the companies that manufacture the vaccines. “In the RCTs with the longest possible blinded follow-up, mRNA vaccines had no effect on overall mortality despite protecting against some COVID-19 deaths. On the other hand, the adenovirus-vector vaccines were associated with lower overall mortality,” researchers said. Is this re-analysis accurate and trustworthy? What is the conclusion we should draw from this work?
ClosedNicola asked 11 months ago • 
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There is a headline on news stories saying: “The Omicron XBB.1.5 variant of COVID-19 is more likely to infect individuals who have been vaccinated, according to New York City health officials.” The NYC Department of Health and Mental Hygiene wrote on Twitter on Jan. 13: “Omicron subvariant XBB.1.5 now accounts for 73 percent of all sequenced COVID-19 cases in NYC. XBB.1.5 is the most transmissible form of COVID-19 that we know of to date and may be more likely to infect people who have been vaccinated or already had COVID-19.” Despite this, the department urged New Yorkers to get vaccinated and receive the updated COVID-19 booster shot, stating that doing so “is still the best way to protect yourself from hospitalization and death from COVID-19, including from these new variants.” It is written in a way that suggests there is increased susceptibility to infection caused by prior vaccination. Is that correct?
ClosedNicola asked 1 year ago • 
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A viewer asks: “Creator, is there any truth about a new variant of the Omicron virus, named XBB, claimed to be the most deadly virus so far in the 21st century?”
ClosedNicola asked 1 year ago • 
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There are reports that infections with the new Omicron strains of Covid-19 are more severe in previously vaccinated individuals. Is that true, and due to impaired Type I interferon?
ClosedNicola asked 2 years ago • 
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The Covid-19 vaccines and boosters clearly do not prevent infection or transmission of the newer Omicron strains, B.4 and B.5. Now, with the possibility of vaccination causing more severe symptoms with the new strains, is it time to retire the vaccines?
ClosedNicola asked 2 years ago • 
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