DWQA Questions › Tag: clinical trialsFilter:AllOpenResolvedClosedUnansweredSort byViewsAnswersVotesA study just completed in the U.S. and Canada of 821 health care workers exposed to people with COVID-19 infections failed to show a statistically significant benefit of hydroxychloroquine in preventing infections (11.8% with hydroxychloroquine versus 14.3% of placebo group became ill). There was also no significant lessening of disease severity once they became symptomatic. How can the data be explained in view of your support for hydroxychloroquine use?ClosedNicola asked 5 years ago • Coronavirus COVID-19478 views0 answers0 votesThe New England Journal of Medicine just published a non-randomized study of hydroxychloroquine coupled with azithromycin in patients with moderate to severe COVID-19 infections, showing no benefit compared to a control group, using intubation or death as endpoints. Can you comment on the prospects for this therapy, in light of this study and your prior endorsement of this treatment?ClosedNicola asked 5 years ago • Coronavirus COVID-19433 views0 answers0 votesIs the recent small study combining azithromycin with hydroxychloroquine in treating coronavirus COVID-19 accurate in reflecting significant clinical benefit due to both anti-inflammatory and antiviral replication activities? Will this be a valuable adjunct in reducing the impact of the pandemic?ClosedNicola asked 6 years ago • Coronavirus COVID-19581 views0 answers0 votes