There is no upper limit in terms of safety. There is no need to have all water be of such a source, but regular intake will keep up a sufficient level of these novel organisms so their function is supported as a part of the life balance. So we cannot give you a strict dosing with respect to volume and frequency, it will vary, depending on the nature of the water and its content of life forms. Some water has a very, very high concentration, other water has but a meager presence so more ingestion over time is needed for the ideal number to build up within the body. So we would say some daily ingestion of ideal water is a good idea because one will never know the true quality of their particular source and it is better to be safe than sorry.