He asks: “Or at least can Creator heal/mitigate/transmute any adverse reactions if my wife does have her suspicious breast mass drained and biopsied, to heal it to benign status?”

Here again, if the decision is made to have the medical evaluation proceed to obtain a more precise look at things and have a basis for making a sound judgment about possible secondary measures, to get prayer and healing requests going now can only help to get ahead of any karmic liabilities that would tend to complicate things, either by stirring up additional negativity that could pile on, as well as making inroads to work against any shortfall with respect to belief quotients of the recipient, if only as a consequence of inner fear in facing a difficult situation with an uncertain future outcome.