Some of the ingredients in Ultimate Bone Support by Advanced Bionutritionals are at lower levels than used in clinical studies establishing their effects when used singly. Does that not matter or is there a synergy from the overall combination of ingredients?

Both of these possibilities are correctly addressing the reality here. High concentrations in the ranges used in single agent clinical studies are not necessary in order for this supplement to promote general health and well-being over a span of time which will help fill in a shortfall because of the vagaries of human nutrition. When people, again and again, have extended periods with subpar intake of critical biochemical nutrients and, together with a decline in overall vigor of the physiology which will take a toll on the ruggedness of human tissues and organs in standing up to the ravages of time, these ingredients do indeed also work synergistically. And so, the combination will be allowing for a benefit to accrue through chronic use of the supplement without causing an unnatural imbalance from an over-dose of any particular one of the ingredients.